When you multiply two numbers, the unit digit of the answer depends only on the unit digits of the numbers you multiplied. That single fact makes these questions easy. To find the last digit of 243¹⁷, you never need 243 itself; you only need 3¹⁷, and in fact only the last digit of that.
Keep multiplying a digit by itself and the unit digits soon start repeating. For 2 the sequence of unit digits is 2, 4, 8, 6, 2, 4, 8, 6 and so on. The repeating block is called the cycle, and its length is the cyclicity. Once you know the cycle, any power is a matter of finding the right position in it.