DI sets in bank exams are built so that exact calculation of every question takes too long. The options, however, are usually far enough apart that a careful estimate is enough. The skill is to round in a way that keeps the error smaller than the gap between options.
The rule that keeps approximation safe: read the options before you calculate. If they are widely spread, round both numbers to friendly values. If two options are close, keep more digits for the step that decides between them.
A useful way to judge this is to think in terms of relative error. Rounding 4,812 to 4,800 changes it by about 0.25%, which is harmless when the options differ by 5% or more. Rounding 4,812 to 5,000 changes it by about 4%, which can push you onto the wrong option. As a rough guide, keep each rounding within about 1% of the original number unless the options are very far apart, and never round the same number twice in one calculation.
Approximation also helps you check exact work. If you calculate 18% of 4,250 and get 7,650, a quick estimate of "a bit under one-fifth of 4,250, so about 800" tells you immediately that a decimal point has slipped.